Cleveland Browns · DE
Isaiah McGuire recorded 34 indexed regular-season NFL appearances across 4 rostered seasons with Cleveland Browns.
2.2
tackles/gm
0
playoff games
4
indexed seasons
34
career games
Five defining games
A provisional five-game introduction to Isaiah McGuire's most significant indexed performances.
Cincinnati Bengals vs Cleveland Browns
Regular Season · Sep 7, 2025
6 tackles · 1 sacks · 0 INT
Cleveland Browns vs Cincinnati Bengals
Regular Season · Jan 7, 2024
4 tackles · 1 sacks · 0 INT
Cleveland Browns vs Las Vegas Raiders
Regular Season · Nov 23, 2025
6 tackles · 1 sacks · 0 INT
Single-game peaks
Position-relevant single-game records from Isaiah McGuire's indexed NFL box scores.
Career high: 6 total tackles
Cleveland Browns vs Las Vegas Raiders
Regular Season · Nov 23, 2025
6 tackles · 1 sacks · 0 INT
Career high: 1 sack
Pittsburgh Steelers vs Cleveland Browns
Regular Season · Oct 1, 2026
3 tackles · 1 sacks · 0 INT
Career high: 2 tackles for loss
Carolina Panthers vs Cleveland Browns
Regular Season · Sep 27, 2026
2 tackles · 1 sacks · 0 INT
Career high: 3 quarterback hits
Miami Dolphins vs Cleveland Browns
Regular Season · Dec 29, 2024
3 tackles · 1 sacks · 0 INT
Career high: 1 forced fumble
Minnesota Vikings vs Cleveland Browns
Regular Season · Oct 5, 2025
0 tackles · 0 sacks · 0 INT
Career chapters
Follow the team eras that shaped Isaiah McGuire's career, in chronological order.
Earliest → latest
Official awards via ESPN · Pro Bowl and All-Pro counts via NFLverse with selection years cross-checked against Wikipedia · league leads verified from indexed regular-season stats