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Tyquan Lewis

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Indianapolis Colts · DE

Tyquan Lewis recorded 69 indexed regular-season NFL appearances across 8 rostered seasons with Indianapolis Colts.

▶Best highlights

1.6

tackles/gm

1

playoff games

8

indexed seasons

69

career games

Five defining games

Start here

A provisional five-game introduction to Tyquan Lewis's most significant indexed performances.

INDIANAPOLISCOLTS

TENNESSEETITANS

Indianapolis Colts vs Tennessee Titans

Regular Season · Sep 21, 2025

2 tackles · 2 sacks · 0 INT

INDIANAPOLISCOLTS

Indianapolis Colts vs Detroit Lions

Regular Season · Nov 1, 2020

2 tackles · 2 sacks · 0 INT

INDIANAPOLISCOLTS

Dallas Cowboys vs Indianapolis Colts

Regular Season · Dec 16, 2018

3 tackles · 2 sacks · 0 INT

INDIANAPOLISCOLTS

Indianapolis Colts vs Buffalo Bills

Wild Card · Jan 9, 2021

3 tackles · 0 sacks · 0 INT

INDIANAPOLISCOLTS

BALTIMORERAVENS

Indianapolis Colts vs Baltimore Ravens

Regular Season · Oct 11, 2021

4 tackles · 1.5 sacks · 0 INT

Single-game peaks

Career highs

Position-relevant single-game records from Tyquan Lewis's indexed NFL box scores.

Career high: 5 total tackles

INDIANAPOLISCOLTS

Houston Texans vs Indianapolis Colts

Regular Season · Sep 8, 2024

5 tackles · 1 sacks · 0 INT

Career highs: 2 sacks · 3 tackles for loss

INDIANAPOLISCOLTS

TENNESSEETITANS

Indianapolis Colts vs Tennessee Titans

Regular Season · Sep 21, 2025

2 tackles · 2 sacks · 0 INT

Career high: 3 quarterback hits

TENNESSEETITANS

INDIANAPOLISCOLTS

Tennessee Titans vs Indianapolis Colts

Regular Season · Oct 8, 2023

0 tackles · 0 sacks · 0 INT

Career high: 1 forced fumble

INDIANAPOLISCOLTS

NEW ENGLANDPATRIOTS

Indianapolis Colts vs New England Patriots

Regular Season · Dec 1, 2024

3 tackles · 0 sacks · 0 INT

Career high: 1 interception

TENNESSEETITANS

INDIANAPOLISCOLTS

Tennessee Titans vs Indianapolis Colts

Regular Season · Oct 31, 2021

1 tackles · 1 sacks · 1 INT

Career chapters

Franchise eras

Follow the team eras that shaped Tyquan Lewis's career, in chronological order.

Earliest → latest

Franchise era

2012–2018

A generational successor carries immediate turnarounds

Indianapolis Colts · Andrew Luck's brilliant sprint

Luck reached the playoffs in each of his first three seasons and authored a massive comeback, but accumulated injuries led to his sudden retirement.

Read the era story →

Franchise era

2019–present

Jonathan Taylor

A strong roster searches for quarterback permanence

Indianapolis Colts · Life after Luck

Indianapolis cycled through veteran and young quarterbacks while retaining a physical offensive identity and rebuilding around its line and skill talent.

Read the era story →

Career accomplishments

8 NFL seasons69 career games65 career solo tackles18 career sacksCollege: Ohio StateDrafted by: INDDraft pick: 64Jersey: 941 playoff appearancesFirst appearance: Nov 11, 2018Most recent: Jan 4, 2026

Official awards via ESPN · Pro Bowl and All-Pro counts via NFLverse with selection years cross-checked against Wikipedia · league leads verified from indexed regular-season stats

Team history